Coronavirus patches available soon?

vaccine, but without a needle. Since the beginning of the epidemic, planning to
vaccination Reverse
COVID-19 The spots multiply, indicating a movement that could revolutionize the way vaccines will be given in the future. This technique will be able to avoid a few bursts of tears for some children, who do not like syringes. But above all, it has many other advantages, especially in terms of distribution, or increased efficiency.

A study on mice was published Friday in the journal science progress, showed promising results. Patch used: A 1cm by 1cm square, made of plastic, with over 5,000 tiny peaks on its surface, “so small you can’t even see them,” described Dr David Muller, co-author of the study and a virologist at the University of Queensland, Australia. These tips are coated with the vaccine, which is deposited on the skin when it penetrates.

improve efficiency

Mice were vaccinated with the patch (placed for 2 min), others with needles. For the first category, “We got a very strong antibody response, including in the lungs, which is important COVID-19» Detailed researcher. He says that the results obtained have “largely exceeded” needle vaccination.

Second, the efficacy of a single dose was evaluated. Using an adjuvant that stimulates the immune response, the mice are then “not sick at all.” The vaccines are usually given by intramuscular injection. Dr. Muller explains that muscle does not contain “as many immune cells needed to support a vaccine,” compared to skin.

Additionally, inserting the limbs causes small injuries that alert the body to a problem and thus stimulate an immune response. For the scientist, the advantages of this technology are obvious: first, the vaccine can remain stable for a month at 25 ° C, and a week at 40 ° C (compared to a few hours at room temperature for vaccines). Pfizer or our moderator). This allows for less dependence on the cold chain, which is a ‘challenge for developing countries’.

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Ease and quantity

In addition, it is “very easy to manage”: trained nursing staff is no longer needed. Burak Ozdoganlar, professor of engineering at Carnegie Mellon University in Pittsburgh, US, has been working on these corrections since 2007.

He sees another benefit: “A smaller amount of the vaccine, administered precisely to the skin, can produce an immune response similar to an intramuscular injection,” he says. An important factor as countries struggle for doses. He can produce 300 to 400 patches a day in his lab, but he regrets not being able to test messenger RNA vaccines with Pfizer or Moderna as these groups are not authorized to do so.

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